Procede ameliore de preparation de n-[(s)-ethoxycarbonyl-l-butyl]-(s)-alanine

An improved process for the preparation of n-[(s)-ethoxycarbonyl-l-butyl]-(s)-alanine

Abstract

An improved process for the preparation of N-[(S)-ethoxy carbonyl-l-butyl]-(S)-alanine by simple hydrogen gas bubbling in the reaction mixture at atmospheric pressure or in slight negative pressure in presence of palladium carbon at low temperature.
L'invention concerne un procédé amélioré de préparation de N-[(S)-éthoxycarbonyl-1-butyl]-(S)-alanine par simple barbotage d'hydrogène dans le mélange de réaction à la pression atmosphérique ou à une pression légèrement négative en présence de palladium-carbone à basse température.

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Patent Citations (2)

    Publication numberPublication dateAssigneeTitle
    EP-0308340-A1March 22, 1989Adir Et CompagnieProcess for the synthesis of N-alkylated alpha-amino acids and their esters, use in the synthesis of carboxyalkyl dipeptides
    US-2003045744-A1March 06, 2003Jean-Claude SouvieNovel method for synthesis of n-[(s)-1-carboxybutyl]-(s)-alanine esters and use in synthesis of perindopril

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